学科服务 更多>>

关键词： Spatial heterodyne spectroscopy   Raman spectroscopy   diode-pumped solid-state   DPSS   chemical analysis  

摘要： Spatial heterodyne spectroscopy (SHS) is used for quantitative analysis and classification of liquid samples. SHS is a version of a Michelson interferometer with no moving parts and with diffraction gratings in place of mirrors. The instrument converts frequency-resolved information into a spatially resolved one and records it in the form of interferograms. The back-extraction of spectral information is done by the fast Fourier transform. A SHS instrument is constructed with the resolving power 5000 and spectral range 522-593 nm. Two original technical solutions are used as compared to previous SHS instruments: the use of a high-frequency diode-pumped solid-state laser for excitation of Raman spectra and a microscope-based collection system. Raman spectra are excited at 532 nm at the repetition rate 80 kHz. Raman shifts between 330 cm(-1) and 1600 cm(-1) are measured. A new application of SHS is demonstrated: for the first time, it is used for quantitative Raman analysis to determine concentrations of cyclohexane in isopropanol and glycerol in water. Two calibration strategies are employed: univariate based on the construction of a calibration plot and multivariate based on partial least squares regression. The detection limits for both cyclohexane in isopropanol and glycerol in water are at a 0.5 mass% level. In addition to the Raman-SHS chemical analysis, classification of industrial oils (biodiesel, poly(1-decene), gasoline, heavy oil IFO380, polybutenes, and lubricant) is performed using the Raman-fluorescence spectra of the oils and principal component analysis. The oils are easily discriminated showing distinct non-overlapping patterns in the principal component space.

关键词： 检验分析   安全生产   作用  

摘要： 在化工生产过程中存在许多复杂的工艺环节,并且会应用到各种各样的化工材料,这就导致化工生产过程中存在较多的安全风险,如果得不到有效的控制,极易引发安全事故。因此在化工生产中非常重视检验分析工作,通过检验分析可以有效掌握化工生产中的各种安全隐患因素,及时消除这些隐患因素的影响。因此文章就对当下化工生产中检验分析的重要作用进行了探究分析,并提出了相关建议和看法,以供借鉴。

关键词： Biomarkers   Single-sample   Classification   Cancer   RNA-Seq   Microarray  

摘要： Background High-throughput gene expression profiles have allowed discovery of potential biomarkers enabling early diagnosis, prognosis and developing individualized treatment. However, it remains a challenge to identify a set of reliable and reproducible biomarkers across various gene expression platforms and laboratories for single sample diagnosis and prognosis. We address this need with our Data-Driven Reference (DDR) approach, which employs stably expressed housekeeping genes as references to eliminate platform-specific biases and non-biological variabilities. Results Our method identifies biomarkers with "built-in" features, and these features can be interpreted consistently regardless of profiling technology, which enable classification of single-sample independent of platforms. Validation with RNA-seq data of blood platelets shows that DDR achieves the superior performance in classification of six different tumor types as well as molecular target statuses (such as MET or HER2-positive, and mutant KRAS, EGFR or PIK3CA) with smaller sets of biomarkers. We demonstrate on the three microarray datasets that our method is capable of identifying robust biomarkers for subgrouping medulloblastoma samples with data perturbation due to different microarray platforms. In addition to identifying the majority of subgroup-specific biomarkers in CodeSet of nanoString, some potential new biomarkers for subgrouping medulloblastoma were detected by our method. Conclusions In this study, we present a simple, yet powerful data-driven method which contributes significantly to identification of robust cross-platform gene signature for disease classification of single-patient to facilitate precision medicine. In addition, our method provides a new strategy for transcriptome analysis.

关键词： 区域医疗联合体   协作运营   医学检验服务支撑平台  

摘要： 近年来,随着各地各种形式的医疗联合体(medicalconsortium)建设的不断推进,医疗联合体的社会关注度越来越高。医疗信息交换,相互承认结果,样品运输问题,比如友谊医院每个成员单位介绍了医学检验在对联的联合医疗服务支持平台,一种新型的医学测试,探索一种“合作”服务模式,实现“六统一”要求,对联医疗的实现优势互补,资源优化配置。基于多角度医疗联盟治理结构的对联,竞争和合作方式,健康促进和健康服务,改善和政府之间的利益,市场和第三方组织和相位差异的因素进行了分析,为了进一步促进服务,责任,合作和利益联盟的管理集成医疗卫生发展的对联。

关键词： 实验室检验   方法内容   临床诊断   作用意义  

摘要： 分析实验室检验在兽医临床诊断中应用作用。通过对2015年1月~2018年10月翻阅实验室检验相关应用文献与资料,对其总结、整理归纳。表明实验室检验在兽医临床诊断中具有显著效果,为动物疫情与患病动物检验提供了可靠的依据。说明实验室检验在兽医临床诊断中是必不可缺的重要环节,可以有效帮助兽医进行疫情监测与改善免疫抗体等,并且促进传统兽医诊断向现代化医疗转型。

关键词： 医院感染   临床微生物检验与监测   控制效果   满意度  

摘要： 目的探讨临床微生物检验与监测在控制医院感染中的作用。方法选取我院82例患者纳入研究,采用计算机随机数字表法将患者分为对照组与观察组,对照组患者使用常规方法对感染进行控制,观察组患者使用微生物检验与监测方式对感染进行控制。比较2组患者的感染发生情况以及满意度。结果观察组患者感染发生情况、满意度均显著优于对照组(P<0.05)。结论使用临床微生物检验与监测方式对医院感染进行控制的效果较好,可显著降低感染发生率,改善患者的生存状态,促进治疗的顺利开展,并提高患者的满意度,可以在临床上广泛应用。

关键词： 化工分析   化工检验   重要作用  

摘要： 在进行化工生产时,化工分析以及化工检测都是其中非常重要的组成部分,要想使我国当前的化工生产得到进一步的提升,就必须要在完善化工分析以及改进化工检测方面上来进行。化工分析是化工企业在进行生产管理时的重要工作,它有助于化工企业减少在能源上的消耗、消除污染。所以,化工企业在进行生产的过程中,对化工分析以及化工检验展开有效的应用,是化工企业对生产管理做出进一步的优化与调整的重要举措。

关键词： 生化检验   肝硬化   诊断   作用  

摘要： 目的分析生化检验指标在肝硬化疾病诊断中的作用。方法选择80例肝硬化患者作为A组, 80例体检健康者作为B组。对比两组研究对象的谷丙转氨酶(ALT)、谷草转氨酸(AST)、碱性磷酸酶(ALP)、血清γ谷氨酰转肽酶(GGT)、血清总胆固醇(TC)水平。结果A组研究对象ALT、AST、ALP、GGT、TC分别为(56.22±10.49)U/L、(96.52±14.57)U/L、(180.51±22.49)U/L、(177.61±24.27)U/L、(6.80±0.34)mmol/L,均高于对照组的(15.61±2.92)U/L、(16.08±2.49)U/L、(76.21±10.56)U/L、(18.59±8.11)U/L、(4.20±0.29)mmol/L,差异均有统计学意义(P<0.05)。结论在临床肝硬化的诊断中,通过分析生化检验指标,可以更加准确地了解患者的病情,做好预后措施,临床应用效果好,值得推广。

关键词： 低碳经济   高校快递包装   分类回收   再利用  

摘要： 如今网络购物已成为人们生活不可或缺的一部分,网购业务与日俱增,使我国快递包裹数量已居于世界第一位。由于快递包装回收体系不完善,消费者垃圾分类回收利用意识不强,快递包装废弃物引发的资源浪费和环境污染问题日益严重。基于这种现状,以湖州师范学院为例,通过问卷调查分析高校快递包装现状以及回收再利用存在的问题,以生态经济为视角,促进资源共享、解决包装垃圾问题为目的构建合理的回收机制,为高校快递包装回收再利用提出建议。